Armed with a PhD in Economics from the London School of Economics and Political Science in 1962, economist Jayanta Madhab retired as the Director of the Asian Development Bank (ADB). After retirement, when the Govt. of India opened up the banking sector to the private sector, applied and got a license to set up a new bank, which was set up in the name of Global Trust Bank with the partnership of World Bank Group, Asian Development Bank, and other international financial Institutions. One year after that Manmohan Singh, who was the finance minister at that time (around 1994-95) wanted to start up a financial organization for the Northeast India. So, in the year 1995 NEDFi (North Eastern Development Finance Corporation Ltd) was set up and he was appointed the Chairman.

Till now it has grown into a huge organization. He was associated with the RGVN (Rashtriya Gramin Vikas Nidhi) as the Chairperson from 2006-2012. He had been member of many national and international Finance commissions. He spends half of the time in Delhi looking after the Central Government Projects_ as the Chairman of the Advisory Commission of NMBA (National Mission on Bamboo Application), where they help transforming bamboo into different materials, as the Chairman of Asha Bharti, an association which is trying to bridge the understanding gap between India and South-East Asia and Central Asia. He spent twenty three years outside India and since 1958 he had been outside Assam. He wanted to know Assam and North-East and work for the development of the region. He wrote a number of economic articles in "Economic Times". Now he wants to devote time in writing as he is planning to work on his autobiography.

Anindita Das interviewed him on the potential of Guwahati city as a business capital